Special skin for radiotherapy and pressure sores

Special skin for radiotherapy and pressure sores-


Introduction

In 2016, approximately 1,700,000 new cases of cancer were diagnosed. It is estimated that the number of new cases of cancer is 484 per 100,000. The number of patients living beyond their cancer diagnosis is estimated to be 14.5 million in 2014 and is expected to be 19 million by 2024.

It is estimated that half of the patients with cancer will receive radiation therapy, with skin injuries due to radiation therapy occurring in approximately 95%. Also, accidental and occupational exposure to radiation contributes to a number of patients with radiation injuries and skin.

Management of acute or chronic skin injuries due to ionizing radiation is a complex challenge with injuries ranging from acute redness to chronic wounds that cannot be visualized.

Chronic manifestations of radiation injuries may include radiation-induced fibrosis of the skin, nonhealing ulcers, osteoradionecrosis, compromised muscle flaps, and dehiscence of surgical closures.

Etiology

A constant state of skin renewal that occurs approximately every 26 days makes the skin more vulnerable than any other organ to ionizing radiation injury. Ionizing radiation creates free radicals and reactive oxygen intermediates that lead to DNA and protein damage, as well as damage to cellular membranes of rapidly proliferating tissue. (Ruth Bryant and Denise Nix. Acute and Chronic Wounds, Current Management Concepts. 5th Edition. St. Louis, Missouri: Elsevier; 2016.)

Epidemiology

Skin injuries ranging from erythema to full chronic wounds occur in about 95% of patients who undergo radiation therapy. Occupational and accidental radiation exposure are also risk factors for radiation injury. The areas of the body that are more susceptible to radiation injury are the skin of the face, neck, trunk, and extremities.

Treatment / Management
In general, the treatment of radiation injury to the skin, acute, subacute or delayed, should reflect the extent of the injury itself, keeping in mind that necrotic tissue should be debrided, infection and inflammation should be managed properly, moisture management should not be ignored and continuous evaluation of the progression of the wound given the therapy employed should be done regularly with a treatment modality change depending on the status of the reepithelialization progress. In other words, standard wound management concepts should still be applied, with strict modifications given the etiology of the of the injury itself, ether just acute erythema at the skin or full thickness chronic wound.

Special attentio ;-all general duty assistant courses examination mode is ONLINE/OFFLINE also

Fee submit online mode,

Contact us :-D/354 Vibhuti Khand Gomtinagar,Luckno 226010

Visit us :-www.rhec.in

Phone No :-522-4001166,9415787135,6388843372,7355268808